Treatment of Autoimmune Neuromuscular Diseases with High-Dose Intravenous Immune Globulin
نویسندگان
چکیده
منابع مشابه
Intravenous immune globulin in autoimmune and inflammatory diseases.
The Authors Reply: Both these letters ask whether there could be different interpretations of our results. In response to Thomas et al.: we first want to stress that we never claimed “a causal relationship between lower rates of criminality and pharmacologic treatment for ADHD.” However, we do think that the most plausible explanation is that medication reduces the risk. Thomas et al. argue tha...
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PURPOSE A case of acute stroke in a patient who was receiving high-dose intravenous immune globulin (IVIG) for dermatomyositis is reported. SUMMARY A 43-year-old woman presented with overwhelming proximal weakness and myalgias, swelling in her hands, facial and knee rash, generalized fatigue, numbness in her left arm, and lower-back pain. Physical examination revealed that she had symptoms co...
متن کاملIntravenous immunoglobulin in autoimmune neuromuscular diseases.
CONTEXT Intravenous immunoglobulin (IVIG) enhances immune homeostasis by modulating expression and function of Fc receptors, interfering with activation of complement and production of cytokines, providing anti-idiotypic antibodies, and affecting the activation and effector functions of T and B cells. These mechanisms may explain the effectiveness of IVIG in autoimmune neuromuscular disorders. ...
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High dose cyclophosphamide (HiCY) without stem cell rescue has been shown to induce remissions in patients with severe autoimmune disorders (SADS). However, up to 80% of these patients ultimately relapse. Here we review the outcomes of seven patients treated with two cycles and one patient treated with three cycles of HiCY. The diseases re-treated were scleroderma, multiple sclerosis, three pat...
متن کاملTreatment of neonatal sepsis with intravenous immune globulin.
BACKGROUND Neonatal sepsis is a major cause of death and complications despite antibiotic treatment. Effective adjunctive treatments are needed. Newborn infants are relatively deficient in endogenous immunoglobulin. Meta-analyses of trials of intravenous immune globulin for suspected or proven neonatal sepsis suggest a reduced rate of death from any cause, but the trials have been small and hav...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1993
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199304001-00017